Industries Study Report: Active Pharmaceutical Ingredients and High Potency API Industry

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Active Pharmaceutical Ingredients and High Potency API Industry Restraint Analysis

Active Pharmaceutical Ingredients and High Potency API Industry Data Book - Active Pharmaceutical Ingredients and High Potency Active Pharmaceutical Ingredients Market Size, Share, Trends Analysis, and Segment Forecasts, 2023 - 2030

The global Active Pharmaceutical Ingredients and High Potency API Industry was estimated at USD 233.31 billion in 2021 and is anticipated to increase at a significant CAGR of 6.0% from 2022 to 2030.

Grand View Research’s API and High Potency API industry databook is a collection of market sizing & forecasts insights, regulatory & technology framework, pricing intelligence, competitive benchmarking analyses, macro-environmental analyses studies. Within the purview of the database, such information is systematically analyzed and provided in the form of summary presentations and detailed outlook reports on individual areas of research.

Active Pharmaceutical Ingredients Market Insights

The global active pharmaceutical ingredients market size was estimated at USD 209.71 billion in 2021 and is expected to grow at a compound annual growth rate (CAGR) of 5.9% from 2022 to 2030. Advancements in Active Pharmaceutical Ingredient (API) manufacturing, growth of the biopharmaceutical sector, and an increase in geriatric population are among the key drivers of API market. An increase in prevalence of chronic diseases, such as cardiovascular diseases and cancer, is anticipated to boost market growth.

Increasing prevalence of infectious diseases and hospital-acquired infections is driving market growth. In addition, growing incidence of cardiovascular, genetic, and neurologic disorders is anticipated to act as a high-impact-rendering driver for market growth. Cardiovascular Diseases (CVDs) are the most prevalent causes of death globally. According to WHO, cardiovascular diseases cause death of 17.9 million people per day and are expected to cause approximately 25 million deaths by 2030. Increasing epidemiology of lifestyle, aided with rising number of smokers globally, growing incidence of obesity, and increasing dietary irregularities, are factors likely responsible to propel market growth. A recent report by the United Nations (UN) in May 2023 suggests that there has been a 75% increase in the number of girls and 61% in the number of boys with obesity in Europe.

Outsourcing of APIs has become profitable over in-house production. However, this trend took a different turn during the COVID-19 pandemic. Companies are looking to diversify their API suppliers and manufacturers to different locations instead of outsourcing it to just one manufacturer. In addition, risk mitigation is done using dual sourcing to ensure a continuous supply. Hence, key companies aim to capitalize on this ongoing outsourcing trend with new acquisitions. For instance, in August 2023, EUROAPI announced its deal to acquire BianoGMP to enhance its CDMO expertise in oligonucleotide manufacturing, which is a high-growth industry. This further demonstrates the company’s plans for vertical integration.

Order your copy of the Free Sample of “Active Pharmaceutical Ingredients and High Potency API Industry Data Book - Active Pharmaceutical Ingredients and High Potency Active Pharmaceutical Ingredients Market Size, Share, Trends Analysis, and Segment Forecasts, 2023 - 2030” Data Book, published by Grand View Research

HPAPI Market Growth, by Type of Manufacturer Segment, & Trends, 2017 - 2030 (USD Million)

High Potency API Market Insights

The global high potency active pharmaceutical ingredients market size was estimated at USD 23.60 billion in 2021 and is expected to expand at a compound annual growth rate (CAGR) of 6.2% from 2022 to 2030. High potency active pharmaceutical ingredients (HPAPI) market is witnessing growth due to the factors such as thegrowing applications of HPAPI, increasing prevalence of cancer, and growth of targeted therapies.Rise in the incidence of cancer has resulted in increase in R&D pertaining to anticancer drugs, which is expected to boost the growth of the HPAPI market over the forecast period.

The HPAPI market is experiencing a surge in demand for products with the rise in the adoption of cancer therapeutics. Cancer is considered one of the prominent health hazards due to the increasing number of people being affected by the disease. According to WHO, cancer accounted for 10 million deaths in 2020which equals nearly one in six deaths, making it the leading cause of death worldwide. The research initiatives and the presence of health awareness campaigns are expected to fuel the global HPAPI market growth.

Moreover, market players are focusing on developing novel drugs to meet the growing demand for the production of active ingredients. For instance, in July 2022, for its site in Mourenx, the Novasep-PharmaZell Group invested USD 7.3 million as part of a bigger initiative backed by the "France Relance Plan” to increase API and HPAI production capacity. The production of active pharmaceutical ingredients (APIs), notably the extremely potent medicines (HPAPIs) used to treat cancer, will continue to be in high demand, which will support the expansion of the Mourenx site.

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Active Pharmaceutical Ingredients and High Potency API Industry Data Book Competitive Landscape

Key players operating in the Active Pharmaceutical Ingredients and High Potency API Industry are:

Merck & Co., Inc.
AbbVie, Inc.
Bristol-Myers Squibb Company
Boehringer Ingelheim International GmbH
Cipla, Inc.

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Active Pharmaceutical Ingredients and High Potency API Industry: Restraint Analysis

Access the Global Active Pharmaceutical Ingredients and High Potency API Industry Data Book, 2023 to 2030, compiled with details like market sizing information & forecasts, trade data, pricing intelligence, competitive benchmarking, macro-environmental analyses, and regulatory & technological framework studies

Active Pharmaceutical Ingredients Market Growth & Trends

The global active pharmaceutical ingredients market size is expected to reach USD 352.98 billion by 2030, expanding at a compound annual growth rate (CAGR) of 5.9% during the forecast period, according to a new report by Grand View Research, Inc. The market is driven by the growth of the biopharmaceutical sector, advancements in active pharmaceutical Ingredients (API) manufacturing, and an increase in the geriatric population.

The growth of the captive API segment is propelled by companies investing in solving challenges and developing new chemical ways for the production of APIs in-house. This aids in reducing costs and the risk of contamination. Artificial intelligence and protein synthesis are expected to facilitate faster development with greater control over the process.

The rising prevalence of chronic and lifestyle-based conditions, such as cardiovascular diseases, is accelerating the demand for API. For instance, as per U.S. Pharmacist in 2020, 47% of adults have at least one risk factor that supports cardiovascular disease development. Cardiovascular diseases are one of the global, critical public health burdens driving extensive R&D for APIs in the field.

The active pharmaceutical Ingredients market was positively influenced by the COVID-19 pandemic, as countries and significant players produce large quantities of components to meet the demand for the treatment of COVID-19. As a result of the outbreak, drug companies have changed the companies’ strategies to focus on a larger patient population. To treat coronavirus, the U.S., for example, requested that HCQ be imported from India. The virus has also impacted Canada's medicine supply system, potentially causing complications for patients. The increasing importance of generics, rise in consumption of biopharmaceuticals, and expanding drug research and development activities for drug manufacturing are the primary drivers driving the growth of the market. However, the market's expansion is likely to be hampered by unfavorable drug price control regimes in several countries and high manufacturing costs.

Developing nations like India are receiving an increased preference in the market over dominant API market countries, like China, owing to geopolitical situations. Furthermore, India has quality raw materials and products, a large workforce, a vast distribution network, and government subsidies through the "Make in India" program.

Order your copy of the Free Sample of “Active Pharmaceutical Ingredients and High Potency API Industry Data Book - Active Pharmaceutical Ingredients and High Potency Active Pharmaceutical Ingredients Market Size, Share, Trends Analysis, And Segment Forecasts, 2023 - 2030” Data Book, published by Grand View Research

High Potency Active Pharmaceutical Ingredients Market Growth & Trends

The global high potency active pharmaceutical ingredients market size is expected to reach USD 40.66 billion by 2030 and is expected to expand at a compound annual growth rate (CAGR) of 6.2% from 2023 to 2030, according to a new report by Grand View Research, Inc. The growth of the HPAPI market is attributed to rising incidence of cancer, growing targeted therapies, and increasing application of high potency active pharmaceutical ingredients (HPAPI) in treating target diseases. Rising prevalence of cancer is expected to be a major factor. According to the WHO, cancer is the second leading cause of death, accounting for around 9.9 million deaths in 2020. Due to the growing number of people who contract the disease, cancer is regarded as one of the major health risks. The CDC states that factors such as smoking, obesity, alcohol use, and UV radiation exposure are risk factors for cancer since they contribute to the overall burden of the illness.

With limited treatment options and side effects associated with chemotherapy, there is a rising popularity of targeted therapy as it does not damage non-cancerous cells. In May 2021, Amgen, Inc. received the U.S. FDA approval for the launch of LUMAKRAS for treating patients with KRAS G12C-mutated locally advanced or metastatic NSCLC. LUMAKRAS is the first targeted product for the treatment of G12C-mutated KRAS NSCLC patients. This is likely to increase the demand for HPAPIs in the coming years. Characteristics of these anti-cancerous drugs, such as minimum exposure of drugs to non-cancerous cell and their effectiveness, are contributing to market growth.

Go through the table of content of Active Pharmaceutical Ingredients and High Potency API Industry Data Book to get a better understanding of the Coverage & Scope of the study

Competitive Landscape

Key players operating in the Active Pharmaceutical Ingredients and High Potency API industry are:

Teva Pharmaceutical Industries Ltd.
Albemarle Corporation
Viatris Inc.
Aurobindo Pharma
Sun Pharmaceutical Industries Ltd.

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Active Pharmaceutical Ingredients and High Potency API Industry Growth Restraint Analysis Report by 2030

Access the Global API and High Potency API Industry Data Book, 2023 to 2030, compiled with details like trade data, pricing intelligence, and competitive benchmarking.

API Market Report Highlights

The global active pharmaceutical ingredients market was valued at USD 209.71 billion in 2021 and is anticipated to witness growth at a rate of 5.9% over the forecast period.

Innovative APIs held the largest share of 47.07% in 2022, owing to increasing research and development activities for novel drug development and positive government initiatives
The cardiovascular disease segment held the largest revenue share of 21.54% in 2022, attributed to the rising prevalence of target disease globally
The synthetic API segment dominated the market with the largest revenue share of 72.6% in 2021, owing to the higher availability of raw materials and easier protocols for the synthesis of these molecules
North America accounted for the largest revenue share of 38.80% in 2021 and is expected to maintain its lead over the forecast period. This is attributed to the rising epidemiology of cancer, along with other lifestyle-induced diseases, thus encouraging the R&D activities, thereby boosting the market growth

Top Players Operating in the API Market, 2021

Order your copy of Free Sample of "Active Pharmaceutical Ingredients and High Potency API Industry Data Book - Active Pharmaceutical Ingredients and High Potency Active Pharmaceutical Ingredients Market Size, Share, Trends Analysis, And Segment Forecasts, 2023 - 2030” Data Book, published by Grand View Research

HPAPI Market Report Highlights

The global high potency API market was valued at USD 23.60 billion in 2021 and is anticipated to witness growth at a rate of 6.2% over the forecast period.

In 2022, synthetic segment held a dominant share in the HPAPI market owing to its easier synthesis and effectiveness in treatment offered by synthetic HPAPI
Outsourced segment is projected to grow at the fastest rate over the forecast period owing to the increasing adoption of outsourcing of HPAPI
Innovative HPAPI segment is the highest revenue-generating segment in 2022 owing to the increased focus on R&D.
Oncology segment dominated the overall market owing to the rising cancer incidence worldwide along with an enhanced focus on targeted therapies
Asia Pacific is expected to witness the fastest growth during the forecast period owing to the improved manufacturing facilities and the availability of many generic HPAPI producers

Go through the table of content of API and High Potency API Industry Data Book to get a better understanding of the Coverage & Scope of the study

Competitive Landscape

Competitive rivalry in this market is likely to be high due to increasing interest in small molecules and biologics for the treatment of chronic diseases is attracting industry players. These players have adopted strategies such as acquisitions, collaborations, and expansion of manufacturing units to strengthen their position in the market. Development of targeted therapies over the forecast period is expected to further intensify the competitive rivalry in the market. As part of strategic geographical expansion, many companies are setting up manufacturing plants in Asia Pacific region. In addition, increasing number of companies switch to contract manufacturers for APIs, which is further increasing competitive rivalry.

Key players operating in the API and High Potency API industry are:

Merck & Co., Inc.
AbbVie, Inc.
Bristol-Myers Squibb Company.
Boehringer Ingelheim International GmbH.
Cipla, Inc.
Teva Pharmaceutical Industries Ltd.
Albemarle Corporation
Viatris Inc.
Aurobindo Pharma
Sun Pharmaceutical Industries Ltd.

Check out more Industry Data Books, published by Grand View Research

About Grand View Research

Contact:

Active Pharmaceutical Ingredients and High Potency API Industry Restraint Analysis

Active Pharmaceutical Ingredients and High Potency API Industry: Restraint Analysis

Active Pharmaceutical Ingredients and High Potency API Industry Growth Restraint Analysis Report by 2030

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